/* ============================================================================
   NIH Grant Disruptions 2025 - Interactive Website Styles
   ============================================================================ */

/* CSS Reset & Base Styles */
* {
    margin: 0;
    padding: 0;
    box-sizing: border-box;
}

:root {
    --crimson: #af1e37;
    --dark-gray: #323232;
    --light-gray: #c8c8c8;
    --med-gray: #5a5a5a;
    --white: #ffffff;
    --bg-light: #f9f9f9;
    --shadow: rgba(0, 0, 0, 0.1);
}

body {
    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', 'Helvetica Neue', Arial, sans-serif;
    line-height: 1.6;
    color: var(--dark-gray);
    background-color: var(--white);
}

/* Header Styles */
header {
    background: linear-gradient(135deg, var(--crimson) 0%, #8b1729 100%);
    color: var(--white);
    padding: 2.5rem 2rem;
    text-align: center;
    box-shadow: 0 4px 6px var(--shadow);
}

header h1 {
    font-size: 2.5rem;
    font-weight: 700;
    margin-bottom: 0.5rem;
    text-shadow: 2px 2px 4px rgba(0,0,0,0.2);
}

header .subtitle {
    font-size: 1.2rem;
    font-weight: 300;
    margin-bottom: 0.5rem;
}

header .authors {
    font-size: 1rem;
    font-style: italic;
    margin-top: 1rem;
    opacity: 0.95;
}

/* Navigation */
nav {
    background-color: var(--dark-gray);
    padding: 1rem;
    position: sticky;
    top: 0;
    z-index: 1000;
    box-shadow: 0 2px 4px var(--shadow);
}

nav ul {
    list-style: none;
    display: flex;
    justify-content: center;
    flex-wrap: wrap;
    gap: 2rem;
}

nav a {
    color: var(--white);
    text-decoration: none;
    font-weight: 500;
    transition: color 0.3s ease;
    padding: 0.5rem 1rem;
}

nav a:hover {
    color: var(--crimson);
    background-color: rgba(255,255,255,0.1);
    border-radius: 4px;
}

/* Main Container */
.container {
    max-width: 1200px;
    margin: 0 auto;
    padding: 2rem;
}

/* Section Styles */
section {
    margin-bottom: 4rem;
    padding: 2rem;
    background-color: var(--white);
    border-radius: 8px;
    box-shadow: 0 2px 8px var(--shadow);
}

section h2 {
    color: var(--crimson);
    font-size: 2rem;
    margin-bottom: 1.5rem;
    border-bottom: 3px solid var(--crimson);
    padding-bottom: 0.5rem;
}

section h3 {
    color: var(--dark-gray);
    font-size: 1.5rem;
    margin-top: 2rem;
    margin-bottom: 1rem;
}

/* Abstract Section */
.abstract-section {
    display: flex;
    gap: 2rem;
    align-items: flex-start;
}

.abstract-content {
    flex: 2;
}

.abstract-content p {
    margin-bottom: 1rem;
}

.key-points-box {
    flex: 1;
    background-color: #fff5f5;
    border-left: 5px solid var(--crimson);
    padding: 1.5rem;
    border-radius: 4px;
}

.key-points-box h3 {
    margin-top: 0;
    font-size: 1.2rem;
}

.point {
    margin-bottom: 1rem;
}

.point-label {
    font-weight: 700;
    color: var(--crimson);
}

/* Key Findings Grid */
.key-findings {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(200px, 1fr));
    gap: 1.5rem;
    margin: 2rem 0;
}

.stat-box {
    background: linear-gradient(135deg, var(--bg-light) 0%, var(--white) 100%);
    padding: 2rem;
    border-radius: 8px;
    border-top: 4px solid var(--crimson);
    text-align: center;
    transition: transform 0.3s ease, box-shadow 0.3s ease;
    box-shadow: 0 2px 4px var(--shadow);
}

.stat-box:hover {
    transform: translateY(-5px);
    box-shadow: 0 6px 12px var(--shadow);
}

.stat-box .number {
    font-size: 2.5rem;
    font-weight: 700;
    color: var(--crimson);
    display: block;
}

.stat-box .label {
    font-size: 0.9rem;
    color: var(--med-gray);
    margin-top: 0.5rem;
    font-weight: 500;
}

/* Plot Container */
.plot-container {
    margin: 3rem 0;
    padding: 1.5rem;
    background-color: var(--bg-light);
    border-radius: 8px;
    box-shadow: inset 0 2px 4px var(--shadow);
}

.plot-title {
    font-weight: 700;
    font-size: 1.2rem;
    margin-bottom: 1rem;
    color: var(--dark-gray);
    text-align: center;
}

#plot1, #plot2, #plot3 {
    width: 100%;
    min-height: 500px;
}

/* Data Explorer */
.explorer-controls {
    display: flex;
    gap: 1.5rem;
    flex-wrap: wrap;
    background-color: var(--bg-light);
    padding: 1.5rem;
    border-radius: 8px;
    margin-bottom: 2rem;
}

.control-group {
    flex: 1;
    min-width: 200px;
}

.control-group label {
    display: block;
    font-weight: 600;
    margin-bottom: 0.5rem;
}

.control-group select {
    width: 100%;
    padding: 0.75rem;
    border: 1px solid var(--light-gray);
    border-radius: 4px;
    font-size: 1rem;
}

.btn {
    padding: 0.75rem 1.5rem;
    background-color: var(--crimson);
    color: var(--white);
    border: none;
    border-radius: 4px;
    cursor: pointer;
    font-weight: 600;
    align-self: flex-end;
    transition: background-color 0.3s ease;
}

.btn:hover {
    background-color: #8b1729;
}

/* Tables */
table {
    width: 100%;
    border-collapse: collapse;
    margin: 2rem 0;
    background-color: var(--white);
    box-shadow: 0 2px 4px var(--shadow);
    border-radius: 8px;
    overflow: hidden;
}

thead {
    background-color: var(--crimson);
    color: var(--white);
}

th, td {
    padding: 1rem;
    text-align: left;
    border-bottom: 1px solid var(--light-gray);
}

th {
    font-weight: 600;
    text-transform: uppercase;
    font-size: 0.9rem;
    letter-spacing: 0.5px;
}

tbody tr:hover {
    background-color: var(--bg-light);
}

/* Footer */
footer {
    background-color: var(--dark-gray);
    color: var(--white);
    text-align: center;
    padding: 2.5rem;
    margin-top: 4rem;
}

footer p {
    margin-bottom: 0.5rem;
}

footer a {
    color: var(--crimson);
    text-decoration: none;
}

footer a:hover {
    text-decoration: underline;
}

/* Responsive Design */
@media (max-width: 900px) {
    .abstract-section {
        flex-direction: column;
    }
    
    .key-points-box {
        width: 100%;
    }
}

@media (max-width: 600px) {
    header h1 {
        font-size: 1.8rem;
    }
    
    nav ul {
        gap: 1rem;
    }
    
    .key-findings {
        grid-template-columns: 1fr;
    }
    
    .explorer-controls {
        flex-direction: column;
        gap: 1rem;
    }
    
    .btn {
        align-self: stretch;
    }
}