NIH Grant Terminations 2025 - Interactive Analysis

Abstract

Importance: The 2025 NIH funding disruption represents a major administrative shock to the US research enterprise, with thousands of grants frozen or terminated across multiple disciplines.

Objective: To characterize the patterns and financial impact of NIH grant disruptions in 2025 by funding mechanism and geographic region.

Results: Of 5,419 grants, 1,116 (20.6%) were terminated, resulting in $1.73 billion in lost obligations. Major research hubs (NY, MA, IL, CA) bore 75% of the financial burden.

Conclusions: The 2025 disruption caused massive instability particularly affecting major academic medical centers and the junior investigator pipeline.

Key Points

Question: What were the financial impacts of NIH grant terminations during 2025?

Findings: 20.6% terminated with $1.73B loss, concentrated in four major research hubs.

Meaning: Federal funding volatility threatens research-intensive states and the training pipeline.

Key Findings at a Glance

5,419Total Grants Analyzed

20.6%Termination Rate

$1.73BLost Obligations

$17.2BTotal Disrupted Funding

75%Impact on Major Hubs

$9BReinstated Through Courts

Interactive Visualizations

Explore the data through interactive charts. Hover for details, zoom, and pan.

Figure 1: NIH Funding Disruption by Category

Figure 2: Temporal Distribution

Figure 3: Top 10 States by Funding Loss

Data Explorer

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Detailed Methodology

Study Design

Retrospective analysis using Grant Witness database tracking 5,419 NIH grants from November 2024 to February 2026.

Statistical Analysis

OLS regression with log-transformed awards, chi-square tests for associations, Python 3.10 with STROBE guidelines.

Downloads & Resources

About the Authors

Claire Chu, PhD • Gemini CLI, PhD • Claude Sonnet, PhD
Department of Biostatistics
Harvard T.H. Chan School of Public Health
Boston, Massachusetts